Sertraline (generic for Zoloft®)

Not feeling your best? You’re not alone. Medication isn’t for everyone, but it can be life changing for those who need it. Consult with a psychiatry provider through our platform to help determine whether a medication like Sertraline could be right for you and help you feel like yourself again.
FDA-approved for major depressive disorder
Prescribed by licensed psychiatry providers, if appropriate
Online evaluation and ongoing check-ins
Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.

about this medication

what is sertraline

Sertraline is one of the first SSRI (selective serotonin reuptake inhibitor) antidepressant drugs on the US market. Sertraline is marketed under the brand name Zoloft, which was first FDA approved in 1992, as a treatment of major depressive disorder. Sertraline is a prescription drug.

sertraline uses

Currently, sertraline is FDA-approved to treat major depressive disorder (MDD), as well as obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder, and social anxiety disorder. Not all mental health conditions can be treated by a provider through our platform.

how sertraline works

Researchers believe that sertraline (generic for Zoloft) works by controlling the amount of serotonin that is reabsorbed by nerve cells (aka, neurons) in the brain, which increases the amount of free serotonin in the brain. For people with depression and anxiety disorders, this can help to improve interest in activities or reduce the number of panic attacks.

how to use sertraline

Sertraline should be taken exactly as directed by your healthcare provider. The healthcare provider may need to change the dose of sertraline until it is the right dose for you. Sertraline may be taken with or without food. Abruptly stopping sertraline is generally not recommended, even if you feel better, because serious adverse effects called withdrawal symptoms can occur.

sertraline side effects

The most common side effects of sertraline include: nausea, loss of appetite, diarrhea, or indigestion; dry mouth, increased sweating; tremor or shaking; agitation; feeling tired or fatigued; anxiety; change in sleep habits such as increased sleepiness or having trouble sleeping (insomnia); and sexual problems such as decreased libido and ejaculation failure. Discuss any side effects you experience with your provider.

what to expect

a seamless experience with an online psychiatry provider.


Online psychiatric evaluation

Consult via video chat with an online psychiatry provider, who will evaluate you and assess whether medication is appropriate


Private, ongoing follow-ups and medication management

A few weeks after your first appointment, you’ll have your first follow-up to evaluate whether your treatment plan is working—all on your smartphone


Discreet shipping to your door

If prescribed, your medication will be shipped to your door in low-key packaging

we've got answers

Frequently asked questions about sertraline

how does Sertraline (generic for Zoloft) make you feel?
Sertraline has been shown to be effective in treating depression and anxiety symptoms. Even if you start to feel better, do not stop taking your medication without first talking to your healthcare provider.
how long does it take for Sertraline (generic for Zoloft) to work?
Sertraline was shown to be effective as a treatment for major depressive disorder and other anxiety-related disorders in clinical trials lasting 6-12 weeks. Consult with your healthcare provider if you do not think your condition is getting better.

Important Safety Information

If you're in emotional distress, text HOME to connect with a counselor immediately
If you're having a medical or mental health emergency, call 911 or go to your local ER